Trial Type: Basket Trials

ANBL1531
A Phase 3 Study of 131I-Metaiodobenzylguanidine (131I-MIBG) or ALK Inhibitor Therapy Added to Intensive Therapy for Children With Newly Diagnosed High-Risk Neuroblastoma (NBL)
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: DeNardo, Bradley
BH-P-STOP
A Phase 1 Study of IM-1021 in Participants With Advanced Malignancies
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Olszewski, Adam
BH-P-HARP
A Phase 1, First-in-human (FIH), Multicenter, Open-label Trial of DS9051b in Participants With Advanced or Metastatic Adrenocortical Carcinoma (ACC) and Metastatic Castration-resistant Prostate Cancer (mCRPC)
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Carneiro, Benedito
BH-P-EARTH
A Phase 1b/2a Multi-Center, Dose Escalation and Reference Regimen-Controlled, Multi-Cohort Study to Determine the Safety and Efficacy of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy in Patients With Locally Advanced or Metastatic Cancers Following One or More Prior Therapies
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Hadfield, Matthew
BH-P-FLOAT
A Phase I, First-in-human, Open-label, Dose Escalation Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of BNT317 in Patients With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Carneiro, Benedito
LS-P-IMPACT
A First-in-human, Phase 1/2, Open-label, Multi-center, Dose-escalation, Dose-optimization, and Dose-expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Anti-tumor Activity of PARP1 Selective Inhibitor, IMP1734, as Monotherapy in Patients With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Carneiro, Benedito
LS-P-MAST
A Phase 1/2, Open Label, First-in-human, Dose Escalation and Expansion Study for the Evaluation of Safety, Pharmacokinetics, Pharmacodynamics, and Anti-tumor Activity of SAR445877 Administered as Monotherapy or in Combination With Other Anticancer Therapies in Adults With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Almhanna, Khaldoun
BH-P-LAMP
A Phase 1, Open-label, Multicenter, First-in-Human Trial of DS5361b in Participants With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Carneiro, Benedito
ALTE2131
Triptorelin and Protection of Ovarian Reserve in Adolescents and Young Adults With Cancer
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: DeNardo, Bradley
BH-P-CEDER
A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of NDI-219216 in Patients With Advanced Solid Tumors With/Without Microsatellite Instability and/or Deficient Mismatch Repair
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Carneiro, Benedito