Trial Type: Thoracic

BH-P-CEDER
A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of NDI-219216 in Patients With Advanced Solid Tumors With/Without Microsatellite Instability and/or Deficient Mismatch Repair
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Carneiro, Benedito
SWOGS2205
Ice Compress: Randomized Trial of Limb Cryocompression Versus Continuous Compression Versus Low Cyclic Compression for the Prevention of Taxane-Induced Peripheral Neuropathy
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Graff, Stephanie
LS-P-SODA
Phase 1/2, Open-label, Multicenter, First-in-Human Study of DS-3939a in Subjects With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Carneiro, Benedito
BH-P-RAIN
A Phase Ia/Ib Open-label, Dose-escalation Study to Evaluate the Safety and Pharmacokinetics of ROSE12 as a Single Agent and in Combination With Other Anti-tumor Agents in Patients With Locally Advanced or Metastatic Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Lung, Thoracic
Contact: Safran, Howard
LS-P-FONTANA
A Modular Phase I/IIa, Open-label Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of Ascending Doses of AZD5335 Monotherapy and in Combination With Anti-cancer Agents in Participants With Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Khan, Hina
LS-P-MAST
A Phase 1/2, Open Label, First-in-human, Dose Escalation and Expansion Study for the Evaluation of Safety, Pharmacokinetics, Pharmacodynamics, and Anti-tumor Activity of SAR445877 Administered as Monotherapy or in Combination With Other Anticancer Therapies in Adults With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Almhanna, Khaldoun
ALLIANCE-A081801
Integration of Immunotherapy Into Adjuvant Therapy for Resected NSCLC: ALCHEMIST Chemo-IO (ACCIO)
Protocol Status: OPEN TO ACCRUAL
Trial Type: Lung, Thoracic
Contact: Azzoli, Christopher
BRUOG-431
Prevention of Datopotamab Deruxtecan (TROP-2 Directed ADC) Associated Stomatitis in Patients With HER2-negative Metastatic Breast Cancer or Non-small Cell Lung Cancer Using Dexamethasone Mouthwash: a Single-arm, Phase 2 Trial (TROPION- DM, 2023-ESR-000087)
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Graff, Stephanie
BH-P-LAMP
A Phase 1, Open-label, Multicenter, First-in-Human Trial of DS5361b in Participants With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Carneiro, Benedito
BH-P-SUNRAY-01
SUNRAY-01, A Global Pivotal Study in Participants With KRAS G12C-Mutant, Locally Advanced or Metastatic Non-Small Cell Lung Cancer Comparing First-Line Treatment of LY3537982 and Pembrolizumab vs Placebo and Pembrolizumab in Those With PD-L1 Expression ≥50% or LY3537982 and Pembrolizumab, Pemetrexed, Platinum vs Placebo and Pembrolizumab, Pemetrexed, Platinum Regardless of PD-L1 Expression
Protocol Status: OPEN TO ACCRUAL
Trial Type: Lung, Thoracic
Contact: Azzoli, Christopher