Trial Type: Thoracic

LS-P-HEAT
First-in-Human, Phase 1/1b, Open-label, Multicenter Study of Bifunctional EGFR/TGFβ Fusion Protein BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-Driven Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Contact: Birnbaum, Ariel
BRUOG-397
BrUOG 397: NEO Rad (LOW): Neoadjuvant Low Dose Stereotactic Body Radiotherapy, Ipilimumab and Nivolumab for Patients With Resectable Stage IB – III Non-Small Cell Lung Cancer
Protocol Status: OPEN TO ACCRUAL
Trial Type: Thoracic
Contact: Azzoli, Christopher
LS-P-POPPY
A First-in-Human, Open-label, Multicenter, Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of PYX-201 in Participants With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Contact: Carneiro, Benedito
LS-P-COAST
A Phase 1, 2-Part, Multicenter, First-In-Human Dose-Escalation and Dose-Expansion Study of DS-1103a Combination Therapy in Subjects With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Breast, Thoracic
Contact: Graff, Stephanie
SWOGS2205
Ice Compress: Randomized Trial of Limb Cryocompression Versus Continuous Compression Versus Low Cyclic Compression for the Prevention of Taxane-Induced Peripheral Neuropathy
Protocol Status: OPEN TO ACCRUAL
Contact: Graff, Stephanie
BH-P-LAMP
A Phase 1, Open-label, Multicenter, First-in-Human Trial of DS5361b in Participants With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Contact: Carneiro, Benedito
BH-P-STOP
A Phase 1 Study of IM-1021 in Participants With Advanced Malignancies
Protocol Status: OPEN TO ACCRUAL
Contact: Olszewski, Adam
BH-P-ALTAIR
A Phase Ib/II Open-Label, Multicentre Platform Study Evaluating Novel Combinations in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer
Protocol Status: OPEN TO ACCRUAL
Trial Type: Thoracic
Contact: Khan, Hina
LS-P-PRIMROSE
PRIMROSE: A Modular Phase I/IIa, Multi-centre, Dose Escalation, and Expansion Study of AZD3470, a MTA Cooperative PRMT5 Inhibitor, as Monotherapy and in Combination With Anticancer Agents in Participants With Advanced/Metastatic Solid Tumors That Are MTAP Deficient
Protocol Status: OPEN TO ACCRUAL
Contact: Carneiro, Benedito
BRUOG-431
Prevention of Datopotamab Deruxtecan (TROP-2 Directed ADC) Associated Stomatitis in Patients With HER2-negative Metastatic Breast Cancer or Non-small Cell Lung Cancer Using Dexamethasone Mouthwash: a Single-arm, Phase 2 Trial (TROPION- DM, 2023-ESR-000087)
Protocol Status: OPEN TO ACCRUAL
Trial Type: Breast, Thoracic
Contact: Graff, Stephanie