Trial Type: Early Phase Trials for Multiple Cancer Types

A MODULAR PHASE I/IIa Open-label Study to Assess AZD5335 Monotherapy and in Combination with Anti-Cancer Agents in Solid Tumors

Phase 1/2 Study of Rina-S in Patients with Locally Advanced and/or Metastatic Solid Tumors

A Phase Ib/2 Basket Study of ACR-368 Monotherapy and in Combination with Gemcitabine in Adult Subjects with Platinum Resistant Ovarian Carcinoma, Endometrial Adenocarcinoma and Urothelial Carcinoma Based on Acrivon OncoSignature Status. Trial type: Ovarian, Endometrial, Bladder.

A Randomized Trial of Neratinib alone or in Combination with Palbociclib in patients with HER2+ Gynecologic Cancer and Other Solid Tumors

ComboMATCH Treatment Trial: Palbociclib and Binimetinib in RAS-Mutant Cancers

A Modular Phase I/IIa, Open-label, Multi-center Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of Ascending Doses of AZD5335 Monotherapy and in Combination with Anti-cancer Agents in Participants with Solid Tumors.

A phase 1 open-label, dose-escalation and cohort expansion study of luna18 monotherapy and combination therapy in patients with locally advanced or metastatic solid tumors

A Phase 1 Open-Label Study to Evaluate the Efficacy and Safety of ABBV-400 in Select Advanced Solid Tumor Indications. Trial type: Expansion slots for ESCC (second line), PROC, and HCC.

A First-in-Human, Open-label, Multicenter, Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PYX 106 in Subjects with Advanced Solid Tumors

A Phase 1 Open-Label Study of PF-07934040 as a Single-Agent and in Combination With Other Targeted Agents in Participants with Advanced Solid Tumors Harboring Mutations in the KRAS Gene.