A Phase II Study of Gemcitabine Plus Cisplatin Chemotherapy in Patients with Muscle-Invasive Bladder Cancer with Bladder Preservation for Those Patients Whose Tumors Harbor Deleterious DNA Damage Response (DDR) Gene Alterations
Targeting Androgen Receptor in bladder cancer. A Pilot Study of Degarelix in Combination with Neoadjuvant Gemcitabine and Cisplatin in Muscle-Invasive Bladder Cancer.
This drug causes immune activation by blocking PTPN2/N1. The study drug is given alone and in combination with PD-1 inhibitors. Cohorts in kidney cancer, head and neck, and other solid tumors.