Trial Type: Head and Neck Cancer

LS-P-EAST
A Phase 1 Open-Label Study to Evaluate the Efficacy and Safety of ABBV-400 in Select Advanced Solid Tumor Indications. (ABBV-400 is an antibody drug conjugate targeting c-Met with a topoisomerase 1 (Top1) inhibitor payload.)
Status: Pending
Contact: Alex Raufi, MD
MARS TRIAL
A Phase 3 Multicenter, Randomized, Double-arm, Open-label Study of ASP-1929 Photoimmunotherapy in Combination With Pembrolizumab Versus Standard of Care in the First-line Treatment of Patients With Locoregional Recurrence of Squamous Cell Carcinoma of the Head and Neck (HNSCC) With No Distant Metastases
Status: Pending
Contact: Ariel Birnbaum, MD
BrUOG 435
Head and Neck Cancer study project in the Geriatric Population
Status: Pending
Contact: Iole Ribizzi Akhtar, MD
LS-P-Poppy
LS-P-Poppy: First-in-class antibody-drug conjugate (ADC) targeting fibronectin (PYX-201) for solid tumors
Contact: Benedito Carneiro, MD
ABBCV-CLS-484
This drug causes immune activation by blocking PTPN2/N1. The study drug is given alone and in combination with PD-1 inhibitors. Cohorts in kidney cancer, head and neck, and other solid tumors.
Contact: Benedito Carneiro, MD
HEAT Trial
Bifunctional antibody against EGFR and TGF Beta, alone and in combination with pembrolizumab for Head and neck cancer, NSCLC and anal cancer and cutaneous squamous cell cancer
Contact: Ari Birnbaum, MD