Trial Type: Prostate

BH-P-STEAP2
A Phase I/II Open Label Study to Evaluate the Safety, Cellular Kinetics, and Efficacy of AZD0754, a Chimeric Antigen Receptor (CAR) T-cell Therapy Directed Against STEAP2, in Adult Participants With Metastatic Prostate Cancer: APOLLO
Protocol Status: OPEN TO ACCRUAL
Trial Type: Genitourinary, Prostate
Contact: Carneiro, Benedito
LS-P-AJAR
A Phase 1, Open-Label, Multicenter Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer
Protocol Status: OPEN TO ACCRUAL
Trial Type: Genitourinary, Prostate
Contact: Carneiro, Benedito
LS-P-STEAM
A Phase 1 First-in-Human Study Evaluating Safety, Pharmacokinetics, and Efficacy of ABBV-969 in Adult Subjects With Metastatic Castration-Resistant Prostate Cancer
Protocol Status: OPEN TO ACCRUAL
Trial Type: Genitourinary, Prostate
Contact: Carneiro, Benedito
BH-P-SEACLIFF
A Modular Phase I/IIa, Open-label, Multi-centre Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of AZD0516 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Metastatic Prostate Cancer
Protocol Status: OPEN TO ACCRUAL
Trial Type: Genitourinary, Prostate
Contact: Carneiro, Benedito
BH-P-EVOPAR-PROSTATE02
A Randomised, Double-blind, Placebo-controlled, Phase III Study of Adjuvant Saruparib (AZD5305) in Patients With BRCAm Localised High-Risk Prostate Cancer Receiving Radiotherapy With Androgen Deprivation Therapy (EvoPAR-Prostate02).
Protocol Status: OPEN TO ACCRUAL
Trial Type: Genitourinary, Prostate
Contact: Carneiro, Benedito
CTSU-CCTG-PR26
A Randomized Phase III Clinical Trial for the Addition of Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response
Protocol Status: OPEN TO ACCRUAL
Trial Type: Genitourinary, Prostate
Contact: Santopietro, Ariana
BH-P-INAVOPC
A Phase II, Randomized, Multicenter, Open-Label Study Evaluating the Efficacy and Safety of the Combination of Inavolisib Plus Enzalutamide Versus Physician’s Choice of ARPI or Docetaxel in Patients With Metastatic Castration-Resistant Prostate Cancer
Protocol Status: OPEN TO ACCRUAL
Trial Type: Genitourinary, Prostate
Contact: Carneiro, Benedito
BH-P-CRIUS-1
Phase I/II Dose Escalation & Dose Optimization Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of AZD8359, a CD8-guided T Cell-engaging Antibody That Targets STEAP2, in Adult Participants With Prostate Cancer
Protocol Status: OPEN TO ACCRUAL
Trial Type: Genitourinary, Prostate
Contact: Carneiro, Benedito