Trial Type: Genitourinary

BH-P-PARTHENON
A Modular Open-label, Phase I/IIa Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of Ascending Doses of AZD4956 as Monotherapy, and in Combination With Anti-Cancer Agents in Participants With Advanced/Metastatic Homologous Recombination Repair Defective Solid Tumours
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Carneiro, Benedito
LS-P-M20-431
A Phase 1 Study With ABBV-CLS-484 Alone and in Combination in Subjects With Locally Advanced or Metastatic Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Genitourinary, Kidney
Contact: Carneiro, Benedito
LS-P-IMPACT
A First-in-human, Phase 1/2, Open-label, Multi-center, Dose-escalation, Dose-optimization, and Dose-expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Anti-tumor Activity of PARP1 Selective Inhibitor, IMP1734, as Monotherapy in Patients With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Carneiro, Benedito
SWOGS2205
Ice Compress: Randomized Trial of Limb Cryocompression Versus Continuous Compression Versus Low Cyclic Compression for the Prevention of Taxane-Induced Peripheral Neuropathy
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Graff, Stephanie
ALTE2131
Triptorelin and Protection of Ovarian Reserve in Adolescents and Young Adults With Cancer
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: DeNardo, Bradley
BH-P-TROPION-TU03
A Randomized, Open-Label, Phase 2/3 Study of Datopotamab Deruxtecan (Dato-DXd) Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma (la/mUC) Who Progressed During or After Enfortumab Vedotin (EV) Plus Pembrolizumab Combination Treatment TROPION-Urothelial03 (TU03)
Protocol Status: OPEN TO ACCRUAL
Contact: Lagos, Galina
BH-P-LAMP
A Phase 1, Open-label, Multicenter, First-in-Human Trial of DS5361b in Participants With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Carneiro, Benedito
LS-P-MAST
A Phase 1/2, Open Label, First-in-human, Dose Escalation and Expansion Study for the Evaluation of Safety, Pharmacokinetics, Pharmacodynamics, and Anti-tumor Activity of SAR445877 Administered as Monotherapy or in Combination With Other Anticancer Therapies in Adults With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Almhanna, Khaldoun
BH-P-CEDER
A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of NDI-219216 in Patients With Advanced Solid Tumors With/Without Microsatellite Instability and/or Deficient Mismatch Repair
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Carneiro, Benedito
LS-P-PAINT
ACR-2316-101: Phase 1/2 Study of ACR-2316 in Subjects With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Carneiro, Benedito