Trial Type: Genitourinary

BH-P-CEDER
A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of NDI-219216 in Patients With Advanced Solid Tumors With/Without Microsatellite Instability and/or Deficient Mismatch Repair
Protocol Status: OPEN TO ACCRUAL
Trial Type: Breast, Endocrine Neuroendocrine, Gastrointestinal, Genitourinary, Gynecologic, Head and Neck, Musculoskeletal, Neurologic, Other Hematology, Skin, Thoracic
Contact: Carneiro, Benedito
benedito.carneiro@BrownHealth.org
BH-P-TROPION-TU03
A Randomized, Open-Label, Phase 2/3 Study of Datopotamab Deruxtecan (Dato-DXd) Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma (la/mUC) Who Progressed During or After Enfortumab Vedotin (EV) Plus Pembrolizumab Combination Treatment TROPION-Urothelial03 (TU03)
Protocol Status: OPEN TO ACCRUAL
Trial Type: Genitourinary
Contact: Lagos, Galina
GLagos@BrownHealth.org
LS-P-POPPY
A First-in-Human, Open-label, Multicenter, Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of PYX-201 in Participants With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Breast, Genitourinary, Head and Neck, Thoracic
Contact: Carneiro, Benedito
benedito.carneiro@BrownHealth.org
SWOGS2205
Ice Compress: Randomized Trial of Limb Cryocompression Versus Continuous Compression Versus Low Cyclic Compression for the Prevention of Taxane-Induced Peripheral Neuropathy
Protocol Status: OPEN TO ACCRUAL
Trial Type: Breast, Endocrine Neuroendocrine, Eye, Gastrointestinal, Genitourinary, Gynecologic, Head and Neck, Lymphoma, Musculoskeletal, Neurologic, Skin, Thoracic, Unknown Primary
Contact: Graff, Stephanie
sgraff1@BrownHealth.org
BH-P-STEAP2
A Phase I/II Open Label Study to Evaluate the Safety, Cellular Kinetics, and Efficacy of AZD0754, a Chimeric Antigen Receptor (CAR) T-cell Therapy Directed Against STEAP2, in Adult Participants With Metastatic Prostate Cancer: APOLLO
Protocol Status: OPEN TO ACCRUAL
Trial Type: Genitourinary
Contact: Carneiro, Benedito
benedito.carneiro@BrownHealth.org
BH-P-LAMP
A Phase 1, Open-label, Multicenter, First-in-Human Trial of DS5361b in Participants With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Breast, Gastrointestinal, Genitourinary, Gynecologic, Head and Neck, Thoracic
Contact: Carneiro, Benedito
benedito.carneiro@BrownHealth.org
CTSU-CCTG-PR26
A Randomized Phase III Clinical Trial for the Addition of Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response
Protocol Status: OPEN TO ACCRUAL
Trial Type: Genitourinary
Contact: Santopietro, Ariana
asantopietro@BrownHealth.org
LS-P-STEAM
A Phase 1 First-in-Human Study Evaluating Safety, Pharmacokinetics, and Efficacy of ABBV-969 in Adult Subjects With Metastatic Castration-Resistant Prostate Cancer
Protocol Status: OPEN TO ACCRUAL
Trial Type: Genitourinary
Contact: Carneiro, Benedito
benedito.carneiro@BrownHealth.org
LS-P-IMPACT
A First-in-human, Phase 1/2, Open-label, Multi-center, Dose-escalation, Dose-optimization, and Dose-expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Anti-tumor Activity of PARP1 Selective Inhibitor, IMP1734, as Monotherapy in Patients With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Breast, Gastrointestinal, Genitourinary, Gynecologic
Contact: Carneiro, Benedito
benedito.carneiro@BrownHealth.org
BH-P-INAVOPC
A Phase II, Randomized, Multicenter, Open-Label Study Evaluating the Efficacy and Safety of the Combination of Inavolisib Plus Enzalutamide Versus Physician’s Choice of ARPI or Docetaxel in Patients With Metastatic Castration-Resistant Prostate Cancer
Protocol Status: OPEN TO ACCRUAL
Trial Type: Genitourinary
Contact: Carneiro, Benedito
benedito.carneiro@BrownHealth.org