Trial Type: Gastrointestinal

LS-P-CAPE
A Phase II, Open-label, Multi-centre Study to Evaluate Safety, Tolerability, Efficacy, PK, and Immunogenicity of AZD0901 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Tumours Expressing Claudin 18.2 (CLARITY-PanTumour01)
Protocol Status: OPEN TO ACCRUAL
Contact: Raufi, Alexander
BH-P-SPRINT
An Early Phase Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of PEEL-224 in Patients With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Contact: Safran, Howard
NRG-GI011
A Phase III Randomized Trial of Dose Escalated Radiation in Locally Advanced Pancreas Cancer (LAPC) Patients (LAP100)
Protocol Status: OPEN TO ACCRUAL
Contact: Rogers, Sherise
CMC-CHEMO4METPANC
A Phase 2 Study With Combination Chemotherapy (Gemcitabine and Nab-Paclitaxel), Chemokine (C-X-C) Motif Receptor 4 Inhibitor (BL-8040), and Immune Checkpoint Blockade (Cemiplimab) in METastatic Treatment naïve PANCreas Adenocarcinoma
Protocol Status: OPEN TO ACCRUAL
Contact: Raufi, Alexander
LS-P-GO44479
A Phase II, Open-Label, Multicenter, Randomized Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Patients With Resected Pancreatic Ductal Adenocarcinoma
Protocol Status: OPEN TO ACCRUAL
Contact: Raufi, Alexander
LS-P-OCEAN
A Phase I, Multicenter, Open-Label First in Human Study of Anti-CEACAM5 Antibody Drug Conjugate M9140 in Participants With Advanced Solid Tumors (PROCEADE-CRC-01)
Protocol Status: OPEN TO ACCRUAL
Contact: Breakstone, Rimini
BH-P-ENACT
A Phase 2 Study to Investigate the Efficacy and Safety of Acoustic Cluster Therapy With Modified FOLFIRINOX in Patients With Locally Advanced Pancreatic Cancer
Protocol Status: OPEN TO ACCRUAL
Contact: Raufi, Alexander
BRUOG-430
A Phase II Pilot Study of yttriuM-90 in Combination With capEcitabine and aTezolizumab for oligomEtastatic cOlorectal Cancer With unResectable lIver MeTastasEs (METEORITE)
Protocol Status: OPEN TO ACCRUAL
Contact: Raufi, Alexander
BH-P-SPARK
A Phase 3, Double-blind, Placebo-controlled, Randomized Study to Assess the Efficacy and Safety of ASP3082 in Combination With mFOLFIRINOX or NALIRIFOX as First-line Treatment in Participants With KRAS G12D Mutated Metastatic Pancreatic Adenocarcinoma
Protocol Status: OPEN TO ACCRUAL
Contact: Raufi, Alexander
BH-P-HARMONI-GI3
A Randomized, Active-Controlled, Double-blind, Multicenter, Phase 3 Clinical Study of Ivonescimab in Combination With FOLFOX Versus Bevacizumab in Combination With FOLFOX for the First-line Treatment of Metastatic Colorectal Cancer
Protocol Status: OPEN TO ACCRUAL
Contact: Breakstone, Rimini