Trial Type: Breast

BH-P-STOP
A Phase 1 Study of IM-1021 in Participants With Advanced Malignancies
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Olszewski, Adam
BH-P-PARTHENON
A Modular Open-label, Phase I/IIa Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of Ascending Doses of AZD4956 as Monotherapy, and in Combination With Anti-Cancer Agents in Participants With Advanced/Metastatic Homologous Recombination Repair Defective Solid Tumours
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Carneiro, Benedito
LS-P-POPPY
A First-in-Human, Open-label, Multicenter, Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of PYX-201 in Participants With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Carneiro, Benedito
LS-P-COAST
A Phase 1, 2-Part, Multicenter, First-In-Human Dose-Escalation and Dose-Expansion Study of DS-1103a Combination Therapy in Subjects With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Graff, Stephanie
LS-P-IMPACT
A First-in-human, Phase 1/2, Open-label, Multi-center, Dose-escalation, Dose-optimization, and Dose-expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Anti-tumor Activity of PARP1 Selective Inhibitor, IMP1734, as Monotherapy in Patients With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Carneiro, Benedito
LS-P-EAST
A Phase 1 Open-Label Study to Evaluate the Efficacy and Safety of ABBV-400 in Select Advanced Solid Tumor Indications
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Raufi, Alexander
SWOGS2205
Ice Compress: Randomized Trial of Limb Cryocompression Versus Continuous Compression Versus Low Cyclic Compression for the Prevention of Taxane-Induced Peripheral Neuropathy
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Graff, Stephanie
BH-P-LAMP
A Phase 1, Open-label, Multicenter, First-in-Human Trial of DS5361b in Participants With Advanced Solid Tumors
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Carneiro, Benedito
BH-P-CEDER
A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of NDI-219216 in Patients With Advanced Solid Tumors With/Without Microsatellite Instability and/or Deficient Mismatch Repair
Protocol Status: OPEN TO ACCRUAL
Trial Type: Basket Trials
Contact: Carneiro, Benedito
BH-P-OPERA-2
A Phase 3 Randomized, Double-Blind, Active-Controlled Study of Palazestrant With Ribociclib Versus Letrozole With Ribociclib for the First-Line Treatment of ER+, HER2- Advanced Breast Cancer (OPERA-02)
Protocol Status: OPEN TO ACCRUAL
Trial Type: Breast
Contact: Graff, Stephanie