Trial Type: Head and Neck Cancer

LS-P-Poppy
LS-P-Poppy: First-in-class antibody-drug conjugate (ADC) targeting fibronectin (PYX-201) for solid tumors
Status: Open
Trial Type: Breast Cancer, Early Phase Trials for Multiple Cancer Types, Head and Neck Cancer, Kidney and Bladder Cancer, Lung Cancer, Ovarian Cancer, Pancreas Cancer, Soft Tissue and Bone Cancer
Contact: Dr. Benedito Carneiro
Benedito.carneiro@lifespan.org
ABBCV-CLS-484
This drug causes immune activation by blocking PTPN2/N1. The study drug is given alone and in combination with PD-1 inhibitors. Cohorts in kidney cancer, head and neck, and other solid tumors.
Status: Open
Trial Type: Early Phase Trials for Multiple Cancer Types, Head and Neck Cancer, Kidney and Bladder Cancer
Contact: Dr. Benedito Carneiro
Benedito.carneiro@lifespan.org
HEAT Trial
Bifunctional antibody against EGFR and TGF Beta, alone and in combination with pembrolizumab for Head and neck cancer, NSCLC and anal cancer and cutaneous squamous cell cancer
Status: Open
Trial Type: Early Phase Trials for Multiple Cancer Types, Head and Neck Cancer, Lung Cancer, Melanoma and Skin Cancers
Contact: Dr. Ari Birnbaum
abirnbaum@lifespan.org

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