Trial Type: Kidney and Bladder Cancer

LS-P-MuSIC
A Randomized Phase II, Double-Blind, Multicenter Study Evaluating the Efficacy and Safety of Autogene Cevumeran Plus Nivolumab Versus Placebo Plus Nivolumab as Adjuvant Therapy in Patients with High-Risk Muscle-Invasive Urothelial Carcinoma
Status: Open
Contact: Benedito Carneiro, MD
A031701, PI
A phase II study of Gemcitabine plus Cisplatin Chemotherapy in Patients with Muscle Invasive Bladder Cancer with Bladder Preservation for Those Patients in Whose tumors harbor deleterious DNA damage response (DDR) Gene Alterations
Status: Open
Contact: Galina Lagos, MD
A031701
A Phase II Study of Gemcitabine Plus Cisplatin Chemotherapy in Patients with Muscle-Invasive Bladder Cancer with Bladder Preservation for Those Patients Whose Tumors Harbor Deleterious DNA Damage Response (DDR) Gene Alterations
Status: Open
Contact: Galina Lagos, MD
BrUOG 428
A Pilot Study of Degarelix in Combination with Neoadjuvant Gemcitabine and Cisplatin in Muscle-Invasive Urothelial Cell Carcinoma of the Bladder)
Status: Open
Contact: Sheldon Holder, MD, PhD
LS-P-SODA
LS-P-SODA: Phase I study of antibody-drug-conjugate (DS-3939) targeting tumors expressing TA-MUC-1
Contact: Benedito Carneiro, MD
LS-P-Poppy
First-in-class antibody-drug conjugate (ADC) targeting fibronectin (PYX-201) for solid tumors
Contact: Benedito Carneiro, MD
LS-P-START
A Phase 1/1b, First-In-Human, Multi-Part, Open-Label Trial To Investigate The Safety, Tolerability, Pharmacokinetics, Biological And Clinical Activity Of Df6215 In Patients With Advanced (Unresectable, Recurrent, Or Metastatic) Solid Tumors
Contact: Benedito Carneiro, MD
ABBCV-CLS-484
This drug causes immune activation by blocking PTPN2/N1. The study drug is given alone and in combination with PD-1 inhibitors. Cohorts in kidney cancer, head and neck, and other solid tumors.
Contact: Benedito Carneiro, MD
TIDE
inhibitor of MTAP for patients with MTAP gene alterations in gastric esophageal, NSCLC and bladder cancer
Contact: Benedito Carneiro, MD